Testosterone Therapy In Xxi Century

Nowadays many people are familiar with the appellation of “low testosterone level” What does it mean? It mean that male body produce less amounts of this hormone than necessary

Testosterone is the major androgenic hormone produced by the cells of the testes This hormon regulates gonadotropic secretion and wolffian duct differentiation and stimulates skeletal muscle

There are two different effects of testosterone:

Anabolic effects: promoting growth, muscle building

Androgenic effects: developing the primary (male sex organs) and secondary sex characteristics (deepening of the voice and growth of facial hair for example)

Testosterone level in the body is analysing thrugh the serum total testosterone test

This test measures the total of two forms of testosterone – free and bound Normal test levels of combined bound and free testosterone range anywhere from 300-1100 ng/dl (nanograms per deciliter) depending on age and individual factors Concentration of testosterone much less than 300-1100 ng/dl is to be considered as low testosterone level
Low testosterone level is one of the reasons of male cryptorchidism, hypogonadism and the symptoms of the male climacteric

The quick and effective way to increase level of this hormone in the body is to administer synthetic testosterone

There are few forms of synthetic testosterone:

Injectable forms:

Testosterone Suspension – is an preparation containing free testosterone in a water
Testosterone Enanthate, Cypionate and Propionate – esters of testosterone

Such forms of testosterone are injected in buttocks every one-two weeks
The big disadvantage is that testosterone injections are quite painfull

Oral forms:

Testosterone undecanoate – it is considered a safer oral form of testosterone

One disadvantage of orally administered undecanoate is that it is eliminated from the body very quickly Thus, frequent administration is necessary

Transdermal forms (also known as patches):

In this case testosterone deliver through the skin, by the use of a hormone containing patch, gel, or cream Patch is applied daily to a man’s shaved scrotum, the newer patch forms can be applied to the upper arms, back, thighs, or abdomen

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