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Obesity is not just a cosmetic consideration; it is a dire
health dilemmadirectly harmful to one’s health In the United
States, roughly 300,000 deaths per year are directly related to
obesity, and more than 80% of these deaths arein patients with a
BMI (body mass index, which will be discussed later in
thisarticle) over 30 Obesity also increases the risk of
developing a number ofchronic diseases including:
Insulin Resistance Insulin is necessary for the transport of
blood glucose (sugar) into the cells of muscle and fat (which is
then used forenergy) By transporting glucose into cells,
insulin keeps the blood glucoselevels in the normal range
Insulin resistance (IR) is the condition whereby
theeffectiveness of insulin in transporting glucose (sugar) into
cells isdiminished Fat cells are more insulin resistant than
muscle cells; therefore,one important cause of IR is obesity
The pancreas initially responds to IR byproducing more insulin
As long as the pancreas can produce enough insulin toovercome
this resistance, blood glucose levels remain normal This IR
state(characterized by normal blood glucose levels and high
insulin levels) can lastyears Once the pancreas can no longer
keep up with producing high levels ofinsulin, blood glucose
levels begin to rise, resulting in type 2 diabetes, thusIR is a
pre-diabetes condition In fact scientists now believe that
theatherosclerosis (hardening of the arteries) associated with
diabetes likelydevelops during this IR period
Type 2 (adult-onset) diabetes The risk of type 2 diabetes
increases with the degree and duration of obesity Type 2
diabetes is associated with centralobesity; a person with
central obesity has excess fat around his/her waist, sothat the
body is shaped like an apple
High blood pressure (hypertension) Hypertension is common among
obeseadults A Norwegian study showed that weight gain tended to
increase bloodpressure in women more significantly than in men
The risk of developing highblood pressure is also higher in
obese people who are apple shaped (centralobesity) than in
people who are pear shaped (fat distribution mainly in hips
andthighs)
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